NCT05768165Active, not recruiting
High-intensity Interval Exercise in Rheumatoid Arthritis
Expected Health Benefits on Cardiovascular Function, Inflammation and Quality of Life With High-intensity Interval Exercise for Patients With Rheumatoid Arthritis
Source: ClinicalTrials.gov · Last updated 22 Dec 2025
Brief summary (registry, in English)
Cardiovascular performance and overall fitness can be improved by high-intensity aerobic activity, and these benefits may be achievable by persons with rheumatic diseases. The investigators hypothesize that a 12-week high-intensity interval exercise program will provide substantial improvements in cardiovascular function, inflammation and symptoms affecting quality of life.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 87 (actual)
- First submitted
- 6 Sept 2021
- Start date
- 16 Aug 2021
- Primary completion date
- 30 Jun 2023
- Lead sponsor
- Vastra Gotaland Region
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT05768165
What you commit to
- Study type: Interventional
- Participants enrolled: 87
- From 16 Aug 2021 to the primary completion date, 30 Jun 2023
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cerebrovascular diseases
- Diabetes
- Severe hypertension
- Chronic obstructive pulmonary disease or other severe pulmonary diseases
- Other severe diseases that may be associated with adverse events or restrict participation in high-intensity exercise
Other
- Arthroplasty of large joints
- Inability to manage Cardiopulmonary Exercise Testing (CPET)
- Pregnancy
- Already participating in regular aerobic or strength exercise at a high intensity level (\>1 hours/ week) during the last 6 months
- Inability to speak or read Swedish.
Who the study is looking for
- Rheumatoid arthritis disease according to the American College of Rheumatology (ACR)/ The European Alliance of Associations for Rheumatology (EULAR) 1987/2010 criteria
- Disease duration \>1 year
- Age (range 20-60 years)
- Stable medication on anti- rheumatic drugs for \>3 months
- Low-to-moderate disease activity (\<5.1) according to the Disease activity score 28 (DAS28)
Age in the registry: 20 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sahlgrenska University Hospital Coordinator of this site? Confirm its status | Gothenburg | Sweden | Unknown status |
| Uddevalla Hospital Coordinator of this site? Confirm its status | Uddevalla | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.