NCT05773144Recruiting
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Source: ClinicalTrials.gov · Last updated 7 Jan 2026
Brief summary (registry, in English)
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 219 (estimated)
- First submitted
- 6 Mar 2023
- Start date
- 1 Jun 2023
- Primary completion date
- 1 May 2027
- Lead sponsor
- AdventHealth Translational Research Institute
- Diseases
- Colorectal cancer
- NCT number
- NCT05773144
What you commit to
- Study type: Interventional
- Planned participants: 219
- From 1 Jun 2023 to the primary completion date, 1 May 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Evidence of metastatic colon cancer
- Concurrently actively treated other (non-colon) cancer
- Any other condition that, in the opinion of the investigator, would preclude participation or successful compliance with the protocol
Other
- Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks
- Currently participating in another study with competing outcomes
- Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol
Who the study is looking for
- Age ≥18 years
- Histologically confirmed stage II or III colon cancer
- Completed surgical resection with curative intent
- Plan to initiate chemotherapy
- Engage in \<60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise
- No planned major surgery during the study period
- Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire
- Can walk 400 meters
- Can read and speak English
- Ability to provide written informed consent
- Provide written approval by qualified healthcare professional
- Willing to be randomized
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dana-Farber Cancer Institute Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Kaiser Permanente Northern California Coordinator of this site? Confirm its status | Oakland | United States | Recruiting |
| AdventHealth Coordinator of this site? Confirm its status | Orlando | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.