NCT05773638Recruiting
Cardiovascular and Venous Thromboembolism Disease in Patients with Von Willebrand Disease in the French West
Source: ClinicalTrials.gov · Last updated 6 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Due to increasing of life expectancy, patients with von Willebrand disease are exposed to age-related pathologies such as cancer or cardiovascular diseases. Management of thrombotic events is challenging given the inherent bleeding risk in von Willebrand disease. Few data are currently available in the literature. The aim of the study is to describe the frequency and nature of arterial and venous thromboembolic events and atrial fibrillation in patients with von Willebrand disease in the West of France. The investigators will perform a retrospective multicenter study conducted in the von Willebrand population of the French West. Von Willebrand adult patients followed in one of the French West medical centers participating in the study, who presented deep vein thrombosis, pulmonary embolism, ischemic stroke, transient ischemic attack, acute coronary syndrome, acute limb ischemia, atrial fibrillation, arteriopathy of the lower limbs, angina will be eligible.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 21 Feb 2023
- Start date
- 26 Dec 2021
- Primary completion date
- 26 Dec 2026
- Lead sponsor
- University Hospital, Brest
- Diseases
- Atrial fibrillation
- NCT number
- NCT05773638
What you commit to
- Study type: Observational
- Planned participants: 100
- From 26 Dec 2021 to the primary completion date, 26 Dec 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acquired von Willebrand syndrome
Other
- \- Expression of opposition
- Patients under legal protection
- Minor
Who the study is looking for
- Von Willebrand disease
- Adult
- Followed-up in a reference center of West of France (Caen, Brest, Nantes, Rennes, Le Mans, Angers)
- Consented to be included in BERHLINGO database
- Have presented a thrombotic and/or embolic event or cardiovascular disease including deep vein thrombosis, pulmonary embolism, ischemic stroke, transient ischemic attack, acute coronary syndrome, acute limb ischemia or angina or obliterating arteriopathy of the lower limbs, atrial fibrillation.
- Have not expressed their opposition
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU d Angers Coordinator of this site? Confirm its status | Angers | France | Not yet recruiting |
| CHU de Brest Coordinator of this site? Confirm its status | Brest | France | Recruiting |
| CHU de CAEN Coordinator of this site? Confirm its status | Caen | France | Not yet recruiting |
| CH Le Mans Coordinator of this site? Confirm its status | Le Mans | France | Not yet recruiting |
| CHU de Nantes Coordinator of this site? Confirm its status | Nantes | France | Not yet recruiting |
| CHU de Rennes Coordinator of this site? Confirm its status | Rennes | France | Not yet recruiting |
Related publications
- Venous and Arterial Thrombo-Embolic Events in Patients With von Willebrand Disease From Western France: The TWIGO Study.Haemophilia · 2026 · PMID 42219913
This page is information, not medical advice. Discuss any trial with your doctor.