NCT05778825Active, not recruitingPhase 2
A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors
A Pilot Study of Oral Minoxidil for the Treatment of Persistent Hair Loss in Pediatric, Adolescent, and Young Adult Cancer Survivors
Source: ClinicalTrials.gov · Last updated 20 Feb 2026
Brief summary (registry, in English)
This study will test whether minoxidil taken by mouth (oral minoxidil) can improve hair loss caused by cancer treatment in children and young adults. In addition, the researchers will test the safety of oral minoxidil, and see if the study drug causes few or mild side effects in participants. Other purposes of this study include looking at whether participants are able to follow their study drug dosing schedules, and how oral minoxidil affects participants' quality of life.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 10 Mar 2023
- Start date
- 10 Mar 2023
- Primary completion date
- Mar 2027
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Diseases
- Childhood cancers
- NCT number
- NCT05778825
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 10
- From 10 Mar 2023 to the primary completion date, Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Had a history of alopecia prior to systemic or radiation therapy for cancer, or has alopecia unrelated to cancer treatment.
- Concurrent use of other therapies for alopecia
- Concurrent active anticancer therapies (cytotoxic, targeted, endocrine, immunologic)
Other illness
- Have scalp disorders that preclude the evaluation of alopecia, such as psoriasis
- Has a known hypersensitivity to minoxidil
- History of chronic sclerotic cutaneous GvHD affecting the scalp
- History of orthostatic or symptomatic hypotension, syncope related to hypotension; systolic less than or equal than 100 (for adults) and 90 (for children) at screening.
- Cardiovascular disease that in the opinion of the cardiologist makes the patient unsuitable for therapy
Other
- Active chronic cutaneous GvHD
- Pregnancy.
- Blood pressure less than the 5th percentile or less than 90/50 mmHg for children 10 years or older
Who the study is looking for
- Patients must have been diagnosed with cancer before the age of 17.
- They must have completed either systemic or radiation therapy (cytotoxic chemotherapy and external beam radiation therapy) for their cancer at least 1 year prior to study entry.
- They must be between 6-18 years old at the time of enrollment.
- They must have a clinical diagnosis of persistent or late alopecia for \>6 months and that is definitely, probably, or possibly related to prior chemotherapy and/or radiation.
Age in the registry: 6 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Sloan-Kettering Cancer Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.