NCT05782972Active, not recruitingPhase 4
Therapeutic Response of Sodium-glucose Co-transporter Type-2 Inhibitor in Non-diabetic MAFLD Patients: a Pilot Study
Source: ClinicalTrials.gov · Last updated 3 Mar 2025
Brief summary (registry, in English)
The goal of this single arm, prospective study is to test the therapeutic response of oral dapagliflozin (Forxiga) 10 mg/day for 24 weeks in non-diabetic MAFLD patients. The primary outcomes are the improvement of liver inflammation or fibrosis parameters after 24 weeks treatment. The adverse events were also recorded.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 19 Feb 2023
- Start date
- 11 Mar 2023
- Primary completion date
- 30 Nov 2025
- Lead sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT05782972
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 50
- From 11 Mar 2023 to the primary completion date, 30 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- cancer history
- history of urinary tract infection/genital yeast infection
Lab values
- diabetes history or HbA1C\> 6.5
- eGFR \< 30 ml/min/1.73m2
Other
- systolic blood pressure \< 100 mmHg
Who the study is looking for
- MAFLD patients (hepatic steatosis plus metabolic dysfunction
- ALT elevation (\>35 U/L in male and \>25 U/L in female) or FIB-4 \>=1.45
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Coordinator of this site? Confirm its status | New Taipei City | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.