NCT05783297Completed
Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence
Source: ClinicalTrials.gov · Last updated 4 Jun 2026
Brief summary (registry, in English)
This research study uses a cluster randomized controlled trial design to evaluate the effectiveness of Treatment Text (TXTXT) intervention on adherence and viral load suppression at 3- and 6- months post intervention initiation for youth and young adults with HIV. A total of 12 clinics will be randomized into one of the following two conditions: 1. Comparison Arm (n=6 clinics)- Clinics randomized to the comparison arm will have participants receive the standard of care for 3 months, followed by a 3-month intervention period. 2. Intervention Arm (n=6 clinics)- Clinics randomized to the intervention arm will have participants receive the TXTXT intervention for 6 months.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 210 (actual)
- First submitted
- 17 Jan 2023
- Start date
- 17 Apr 2023
- Primary completion date
- 1 Aug 2025
- Lead sponsor
- Amy K. Johnson, PhD, MSW
- Diseases
- HIV
- NCT number
- NCT05783297
What you commit to
- Study type: Interventional
- Participants enrolled: 210
- From 17 Apr 2023 to the primary completion date, 1 Aug 2025
- 12 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Participant is participating in another study related to ART adherence
- Participants outside of the age range (16-35) will be excluded from the study because this study specifically focuses on youth and young adults living with HIV as they are more likely to disengage from care, delay initiation of ART, and have lower rates of virologic suppression compared to adult populations.
Other
- Participant is unable to give informed consent
Who the study is looking for
- Diagnosed with HIV-infection and on ART regimen for at least one month
- Between 16-35 years of age
- Have a viral load ≥200c/mL and/or report poor adherence (\<90% of pills taken in the last 30 days)
- Able to receive text messages
- Can provide informed consent for research component
- Current patient patient of a participating clinic
Age in the registry: 16 years to 35 years · Sex: All · Does not accept healthy volunteers
Sites (12)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Howard Brown Health Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| University of Illinois at Chicago Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| University of Cincinnati Coordinator of this site? Confirm its status | Cincinnati | United States | Unknown status |
| Corktown Health Center Coordinator of this site? Confirm its status | Detroit | United States | Unknown status |
| Duke University Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| AIDS Healthcare Foundation Coordinator of this site? Confirm its status | Fort Lauderdale | United States | Unknown status |
| Baylor College of Medicine Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Eskenazi Health Coordinator of this site? Confirm its status | Indianapolis | United States | Unknown status |
| Indiana University Coordinator of this site? Confirm its status | Indianapolis | United States | Unknown status |
| KC CARE Health Center Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
| Comprehensive Care Center of Southwest Louisiana Coordinator of this site? Confirm its status | Lake Charles | United States | Unknown status |
| Valley AIDS Council Coordinator of this site? Confirm its status | McAllen | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.