NCT05786235Recruiting
Patients Pregnant Women With or Without Primary Antiphospholipid Antibody Syndrome
Source: ClinicalTrials.gov · Last updated 18 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of the study is to evaluate the ability of placental angiogenesis markers to predict the risk of PE in pregnancy in women with primary APS. To construct reference intervals of placental angiogenesis markers specific to women affected by primary APS in pregnancy by measuring the levels of sFlt-1and PlGF in serum maternal serum and their sFlt-1/PlGF ratio during the trimesters of gestation (I TM, II TM and III TM). For this aim the study will involve recruiting two groups of subjects, one will be cases and one will be controls.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 15 Mar 2023
- Start date
- 6 Dec 2022
- Primary completion date
- 6 Dec 2025
- Lead sponsor
- IRCCS San Raffaele
- NCT number
- NCT05786235
What you commit to
- Study type: Observational
- Planned participants: 60
- From 6 Dec 2022 to the primary completion date, 6 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Group 1
- PMA pregnancies.
- Known chronic pathology in gestational period such as chronic essential hypertension, neurological pathology
- Previous thrombotic event
- Chronic renal failure not related to AD
- Previous history of oncology
- Group 2
- Pregnancy by PMA.
- Previous history of polyabortion and/or late pregnancy complications.
- Known chronic pathology in gestational period such as chronic essential hypertension, neurological pathology
- Previous thrombotic event
- Previous history of oncology
Who the study is looking for
- Group 1
- Pregnant patients between the ages of 18 and 45 years.
- Diagnosis of primary APS, according to international classification criteria.
- Group 2
- Pregnant patients between the ages of 18 and 45 years.
- Patients with at least one previous full-term pregnancy.
- No diagnosis of APS, according to international classification criteria.
Age in the registry: 18 years to 45 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| San Raffaele Hospital Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.