NCT05787522Completed
Clinical Validation of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk
Prospective, Multicenter, Randomized Evaluation of the Performance and Clinical Applicability of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk
Source: ClinicalTrials.gov · Last updated 12 Feb 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate performance and clinical applicability of AI-assisted radiotherapy contouring software (iCurveE) for thoracic organs at risk. The main question it aims to answer is: • Does AI-assisted contouring (AI contouring with manual modification) offer greater accuracy and time efficiency compared to manual contouring? After screening, the qualified participants' thoracic CT images will be anonymized and segmented using three methods: manual, AI (AI-only), and AI-assisted contouring. The researchers will compare the results generated by the three different contouring methods with the ground truth established by expert consensus, in order to evaluate both accuracy and time-related parameters
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 500 (actual)
- First submitted
- 2 Mar 2023
- Start date
- 30 Sept 2022
- Primary completion date
- 27 Jul 2023
- Lead sponsor
- Tianjin Medical University Cancer Institute and Hospital
- Diseases
- Lung cancer, Gastric and esophageal cancer
- NCT number
- NCT05787522
What you commit to
- Study type: Observational
- Participants enrolled: 500
- From 30 Sept 2022 to the primary completion date, 27 Jul 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Congenital malformations or abnormal anatomical structures resulting from non-tumor factors in the scan area.
- Artifact, prosthesis or implantation causing images undistinguishable.
- CT images not conforming to DICOM standards.
- Investigators consider not suitable.
Who the study is looking for
- ≥18 years old, no gender limit.
- Patients diagnosed with breast cancer, lung cancer, or esophageal cancer, who are scheduled for chest CT scanning followed by thoracic radiotherapy.
- CT slice thickness ≤5mm.
- Patients understand the goal of the trial, are willing to attend the trial and sign the informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy Coordinator of this site? Confirm its status | Tianjin | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.