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NCT05787795Recruiting

Identifying and Characterizing Preclinical MS

Source: ClinicalTrials.gov · Last updated 27 Aug 2026

Brief summary (registry, in English)

The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.

Status (registry)
Recruiting
Study type
Observational
Enrollment
1000 (estimated)
First submitted
15 Mar 2023
Start date
21 Jun 2022
Primary completion date
30 Jun 2032
Lead sponsor
Yale University
NCT number
NCT05787795

What you commit to

  • Study type: Observational
  • Planned participants: 1000
  • From 21 Jun 2022 to the primary completion date, 30 Jun 2032
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Ongoing treatment with immunosuppressive medications

Other illness

  • Diagnosis of multiple sclerosis or any ongoing, systemic autoimmune disease

Other

  • Currently pregnant

Who the study is looking for

  • Age 18+
  • Having one or more risk factors for multiple sclerosis, including one or more of the below:
    • Individuals known to have a radiologically isolated syndrome
    • Individuals with a family history of multiple sclerosis (first degree family member)
    • Individuals with personal risk factors, which are known to include smoking, obesity, Epstein Barr virus infections, Vitamin D deficiency, genetic risk score

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Yale University
Coordinator of this site? Confirm its status
North HavenUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.