NCT05787834Recruiting
Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Cancer
Respiratory Muscle Training During Cancer Treatment: Effects on the Autonomic Nervous System and Cardiotoxicity
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
This clinical trial evaluates whether home-based respiratory muscle training is useful for minimizing side effects in patients undergoing treatment for cancer. Over-activation of the nervous system during breast cancer treatment can result in heart- and lung-related side effects which have the potential to reduce a patient's quality of life. Aerobic exercise can help prevent the development of these side effects. However, engaging in regular aerobic exercise may be difficult for breast cancer patients who are actively undergoing treatment. Respiratory muscle training (RMT) involves a series of breathing and other exercises that are performed to improve the function of the respiratory muscles through resistance and endurance training. Home-based RMT may represent a more feasible approach for reducing side effects in patients undergoing treatment for breast cancer.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 130 (estimated)
- First submitted
- 23 Feb 2023
- Start date
- 16 Oct 2023
- Primary completion date
- 16 Oct 2028
- Lead sponsor
- Roswell Park Cancer Institute
- Diseases
- Head and neck cancer, Lung cancer
- NCT number
- NCT05787834
What you commit to
- Study type: Interventional
- Planned participants: 130
- From 16 Oct 2023 to the primary completion date, 16 Oct 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of oral mucosal disease including oral mucositis, or oral candidiasis detected at baseline
- Have uncontrolled intercurrent illness including, but not limited to, ongoing or active respiratory infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, heart failure or psychiatric illness/social situations that would limit compliance with study requirements
- Any condition which in the Investigator's opinion deems the participant an unsuitable candidate to receive study intervention
Who the study is looking for
- Able and willing to provide written informed consent
- Age \>= 21 years old
- Diagnosed with solid tumor (e.g., head and neck, thoracic, or breast cancer)
- Scheduled to receive at least one dose of chemotherapy or immunotherapy or radiation
- Treated at Roswell Park Comprehensive Cancer Center
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Roswell Park Cancer Institute Coordinator of this site? Confirm its status | Buffalo | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.