NCT05788705Completed
Efficacy of JAK STAT Pathways Inhibitors in Treatment of Patients With Rheumatoid Arthritis
Evaluation of the Efficacy of Natural JAK_ STAT Pathways Inhibitors in Treatment of Patients With Rheumatoid Arthritis as a Complementary Medicine
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
There is no treatment that could utterly cure Rheumatoid arthritis (RA), but the disease is mainly improved by conventional disease-modifying anti rheumatic drugs. Methotrexate and biological DMARDs as JAK-STAT inhibitors may be used to control and delay the progression of the disease and improve the quality of lives of patients. However, DMARDs have deleterious effects on human health. Several natural products have been reported to exert inhibitory effects on the JAK-STAT signaling pathway, including green tea extract, chamomile extract, and licorice extract.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 27 Feb 2023
- Start date
- Apr 2025
- Primary completion date
- Jun 2026
- Lead sponsor
- Adel A.Gomaa
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT05788705
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From Apr 2025 to the primary completion date, Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with Malignant tumours,
- Patients with Infectious diseases,
- Patients with Hematologic diseases.
- Patients with other rheumatic diseases.
- Women who are pregnant or breastfeeding.
- Hypersensitivity to dietary supplement used in this study.
- Hypertensive patients
Who the study is looking for
- Male or female,ages18-60.
- Patients who met criteria for the diagnosis of RA
- Patients who were signed the informed consent form.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assiut University Coordinator of this site? Confirm its status | Asyut | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.