NCT05791968Completed
Blood Donation Could Improve Insulin Sensitivity
Effects of a Standard Blood Bank Donation on Insulin Sensitivity in Adults With Pre-diabetes and Abdominal Obesity
Source: ClinicalTrials.gov · Last updated 21 Feb 2025
Brief summary (registry, in English)
Studies in the literature suggest that people with obesity have an excess of stored iron. There is possibly an inverse relationship between ferritin levels and the actions of insulin on glycemic control. The reduction of stored iron by simply donating blood could result in improvements in glycemic control in people with obesity and prediabetes. We propose, to reduce ferritin levels through a standard donation of a unit of whole blood, and to measure if it positively affects glycemic control.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 89 (actual)
- First submitted
- 17 Mar 2023
- Start date
- 15 Sept 2023
- Primary completion date
- 30 Apr 2024
- Lead sponsor
- University of Castilla-La Mancha
- Diseases
- Obesity
- NCT number
- NCT05791968
What you commit to
- Study type: Interventional
- Participants enrolled: 89
- From 15 Sept 2023 to the primary completion date, 30 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- insulin treatment for diabetes
- heart disease
Lab values
- any disease that requires medication that interferes with iron or glucose metabolism
Other
- to not meet donor bank requirements
- anemia
- hereditary hemochromatosis
- familial hypertriglyceridemia or hypobetalipoproteinemia
Who the study is looking for
- have not donated in the last 3 months
- IMC\>25
- fasting blood glucose 100-125 mg/dL
- glycosylated hemoglobin levels between 5.7-6.4%
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Castilla-La Mancha (Exercise Physiology Lab) Coordinator of this site? Confirm its status | Toledo | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.