NCT05793294Active, not recruiting
Child Health, Nutrition and Microbiome Development
Nutritional Status, Health and Gut Microbiome Development in Children; a Prospective Cohort Study From Pakistan
Source: ClinicalTrials.gov · Last updated 5 Jan 2026
Brief summary (registry, in English)
Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children. Emerging evidence suggests that malnourished children have immature gut microbiota compared to age-matched healthy controls and it does not repair even after nutritional interventions. The present study aims to characterize how the gut microbiome develops during the first two years of life in children residing in malnutrition endemic areas of Khyber Pakhtunkhwa, the region with the highest prevalence of childhood malnutrition in Pakistan and the region.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 70 (actual)
- First submitted
- 19 Mar 2023
- Start date
- 10 May 2024
- Primary completion date
- 30 May 2025
- Lead sponsor
- Khyber Medical University Peshawar
- Diseases
- Obesity
- NCT number
- NCT05793294
What you commit to
- Study type: Observational
- Participants enrolled: 70
- From 10 May 2024 to the primary completion date, 30 May 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Infants born with severe acute or chronic medication conditions that require hospitalization or prolonged use of medication or both or the infant is diagnosed with enteropathies.
Age
- Child born to underage (\<18 years old) mother.
Other
- Whose parents refused to provide informed consent to participate in the study.
- Weight of the child is \<1500 gm.
Who the study is looking for
- Healthy infants aged 0 - 28 days
- Born to parents residing in rural and remote areas of District Swat
- Living in separate households
- Parents/caregivers have no plans to move out of the stud site for at least one year after enrollment in the study.
Age in the registry: 1 day to 28 days · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Khyber Medical University Coordinator of this site? Confirm its status | Peshawar | Pakistan | Unknown status |
| Tehsil Matta Coordinator of this site? Confirm its status | Swāt | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.