NCT05793567Not yet recruiting
A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI)
Assessment of Microcirculatory Function in Type 2 Myocardial Infarction
Source: ClinicalTrials.gov · Last updated 31 Aug 2026
Brief summary (registry, in English)
The purpose of this research is to find out if patients with Type 2 Myocardial Infarction (T2MI) without significant epicardial coronary artery disease (CAD) have a greater chance of having coronary microvascular disease (CMD).
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 52 (estimated)
- First submitted
- 20 Mar 2023
- Start date
- Jan 2027
- Primary completion date
- Jan 2028
- Lead sponsor
- Mayo Clinic
- Diseases
- Coronary artery disease
- NCT number
- NCT05793567
What you commit to
- Study type: Observational
- Planned participants: 52
- From Jan 2027 to the primary completion date, Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior coronary artery bypass grafting
- Pregnancy (if sexually active woman of reproductive age, need negative pregnancy test prior to proceeding with coronary angiography - this is standard of care in cath lab)
- Asthma with prior ICU admission due to bronchospasm/need for invasive ventilation
Other illness
- Allergy/contraindication to acetylcholine/adenosine/nitroglycerine products
Other
- Acute coronary event (evidence of plaque rupture, fissure or dissection on coronary angiogram)
- Known to have angiographically significant CAD/pressure wire positive for epicardial CAD
- Inability to receive heparin products
Who the study is looking for
- Ability to give informed consent
- Structurally normal heart (normal LV and RV function, no more than mild valvular heart disease)
- For controls: atypical chest pain with indication for CMD testing
- For T2MI: meet criteria for T2MI according to the 4th Universal definition of MI (rise/fall of troponin with at least 1 value \>99th centile+ evidence of symptoms or signs of myocardial ischemia)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic - Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.