NCT05794620Completed
Faecal Microbiota Analysis in Neurotypical and Autism Syndrome Disorder Siblings
Faecal Microbiota Analysis in Neurotypical and Autism Syndrome Disorder Siblings: FAMILY
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
This study aims to accurately characterise the gut microbiota composition of faeces of children with ASD and compare it with the gut microbiota composition of their neurotypical siblings. In addition it aims to also characterise the metagenome and metabolome of the faeces of both ASD and neurotypical siblings.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 20 (actual)
- First submitted
- 20 Mar 2023
- Start date
- 20 Dec 2022
- Primary completion date
- 8 Apr 2024
- Lead sponsor
- East Suffolk and North Essex NHS Foundation Trust
- Diseases
- Autism
- NCT number
- NCT05794620
What you commit to
- Study type: Observational
- Participants enrolled: 20
- From 20 Dec 2022 to the primary completion date, 8 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of antibiotics in the previous 4 weeks
Age
- Children \<3 years old and \>10 years old
Other
- Not under the care of ESNEFT
- Children that don't have half or full siblings
- Parent/guardian unable to provide informed consent or complete surveys, despite reasonable adjustments being implemented
Who the study is looking for
- Children of both sexes who are diagnosed with ASD and under the care of ESNEFT who have a neurotypical sibling (either full or half sibling), who share their living environment. This is due to the study requiring stool samples that are from siblings, to control for genes and environment where possible.
- Aged 3 years to 10 years old (at time of consent)
- Parent/guardian able to consent to participate
- Parent/guardian able to complete required surveys (or with accommodated adjustments)
Age in the registry: 3 years to 10 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| East Suffolk and North Essex NHS Foundation Trust Coordinator of this site? Confirm its status | Colchester | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.