NCT05801068Completed
Perioperative Management of Factor Xa Inhibitors
Effectiveness and Safety of PERIoperative Factor Xa Inhibitor Discontinuation in Patients With Atrial Fibrillation Who Undergoing Minor Bleeding Risk Elective Procedure or Surgery: A Prospective, Multicenter, Noninterventional Study (PERIXa Study)
Source: ClinicalTrials.gov · Last updated 21 Aug 2026
Brief summary (registry, in English)
This study aims to analyze the safety and effectiveness of the discontinuation/resumption protocol of factor Xa inhibitors before and after invasive procedures/surgeries in non-valvular atrial fibrillation patients who are at risk of minor bleeding in actual clinical settings
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 2500 (actual)
- First submitted
- 3 Mar 2023
- Start date
- 4 Aug 2020
- Primary completion date
- 15 May 2024
- Lead sponsor
- Seoul National University Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT05801068
What you commit to
- Study type: Interventional
- Participants enrolled: 2500
- From 4 Aug 2020 to the primary completion date, 15 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- With antiplatelet drugs
Other illness
- Mental disorder
- Moderate or severe valvular heart disease, or with prosthetic heart valves
- History of systemic embolism or ischemic stroke within the last 12 months
Other
- Pregnancy
- With rivaroxaban or edoxaban at afternoon
- Contraindication to rivaroxaban, apixaban, edoxaban
- scheduled therapeutic endoscopic procedure(s)
Who the study is looking for
- Aged \>20 years
- With rivaroxaban, apixaban, or edoxaban
- History of non-valvular atrial fibrillation
- Scheduled minor bleeding risk procedure(s) (dental procedure, cataract/glaucoma surgery, diagnostic GI endoscopy)
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National university Hostpital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.