NCT05801471Recruiting
Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression
An Observational Prospective Longitudinal Study for the Clinical Evaluation of Visual Field Change in Glaucoma. An Assessment of Different Models of Progression
Source: ClinicalTrials.gov · Last updated 2 Jan 2026
Brief summary (registry, in English)
The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS fundus perimeter and the Humphrey Field Analyzer (HFA) perimeter will be used to assess retinal functionality; an Optical Coherence Tomography (OCT) examination will also be performed to evaluate and obtain clinical information about the structure of the retina.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 7 Mar 2023
- Start date
- 6 May 2022
- Primary completion date
- 6 Nov 2028
- Lead sponsor
- Centervue SpA
- Diseases
- Glaucoma
- NCT number
- NCT05801471
What you commit to
- Study type: Observational
- Planned participants: 200
- From 6 May 2022 to the primary completion date, 6 Nov 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any ocular surgery, except for: uncomplicated cataract surgery and/or glaucoma surgery in both eyes performed within 6 months before enrollment;
- Use of any drug that can interfere with the correct execution of perimetry or that would produce visual field loss;
Other
- Any ocular pathology that can affect visual field other than glaucoma;
- Inability to obtain reliable perimetric examinations;
- Patients with advanced glaucoma for whom, according to the clinician, a 24-2 grid is not advisable to correctly monitor the patient.
Who the study is looking for
- Glaucomatous optic nerve head in both eyes;
- Age between 40 and 90 years;
- Best Corrected Visual Acuity ≤ 0.3 \[logMar\];
- Spherical refraction between -6D and +6D;
- Astigmatism between -2D and +2D.
Age in the registry: 40 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinica oculistica Ospedale San Paolo Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| Glaucoma Research Center, IRCCS Fondazione "G.B. Bietti" Coordinator of this site? Confirm its status | Roma | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.