NCT05804747Completed
A Study to Evaluate Effectiveness and Safety of Edoxaban in Patients 80 Years of Age or Older With Nonvalvular Atrial Fibrillation
A Multicenter, Prospective, Non-interventional Study to Evaluate Effectiveness and Safety of Edoxaban in Patients 80 Years of Age or Older With Nonvalvular Atrial Fibrillation
Source: ClinicalTrials.gov · Last updated 26 Sept 2025
Brief summary (registry, in English)
Non-valvular atrial fibrillation (NVAF) increases the risk of stroke by three- to five-fold, especially in elderly patients, creating a huge burden on medical system as well as a negative impact on patients' lives. Direct oral anticoagulants (DOACs) are recommended for patients with NVAF to prevent strokes. Real world data reveal the underuse of anticoagulation in the elderly, especially due to physicians' concern of bleeding, often neglecting the thromboembolic risk. This study is designed to evaluate the safety and effectiveness of edoxaban in Korean elderly patients with atrial fibrillation.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1204 (actual)
- First submitted
- 27 Mar 2023
- Start date
- 16 Feb 2023
- Primary completion date
- 28 Jul 2025
- Lead sponsor
- Daiichi Sankyo
- Diseases
- Atrial fibrillation
- NCT number
- NCT05804747
What you commit to
- Study type: Observational
- Participants enrolled: 1204
- From 16 Feb 2023 to the primary completion date, 28 Jul 2025
- 33 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Planning to participate or simultaneously participating in any interventional study
- Life expectancy \< 1 year
- No influence on prescribing behavior as participants will only be included in the study after the physicians have made the clinical decision to prescribe edoxaban.
Who the study is looking for
- NVAF participants aged ≥ 80 years old
- Participants who are determined to be prescribed with edoxaban at the discretion of the physician within 8 weeks prior to enrollment according to Package information
- Participants who can return to the site in person for face-to-face visits
- Written informed consent for participation in the study (ICF)
Age in the registry: 80 years to - · Sex: All · Does not accept healthy volunteers
Sites (33)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Korea University Ansan Hospital Coordinator of this site? Confirm its status | Ansan | South Korea | Unknown status |
| Dong-A University Hospital Coordinator of this site? Confirm its status | Busan | South Korea | Unknown status |
| Pusan National University Hospital Coordinator of this site? Confirm its status | Busan | South Korea | Unknown status |
| Samsung Changwon Center Coordinator of this site? Confirm its status | Changwon | South Korea | Unknown status |
| Soonchunhyang University Hospital Coordinator of this site? Confirm its status | Cheonan | South Korea | Unknown status |
| Dankook University Hospital Coordinator of this site? Confirm its status | Cheonan | South Korea | Unknown status |
| Kangwon National University Hospital Coordinator of this site? Confirm its status | Chuncheon | South Korea | Unknown status |
| Keimyung University - Dongsan Medical Center Coordinator of this site? Confirm its status | Daegu | South Korea | Unknown status |
| Catholic University of Korea Daejeon St. Mary's Hospital Coordinator of this site? Confirm its status | Daejeon | South Korea | Unknown status |
| Chungnam University Hospital Coordinator of this site? Confirm its status | Daejeon | South Korea | Unknown status |
| National Health Insurance Service Ilsan Hospital Coordinator of this site? Confirm its status | Goyang | South Korea | Unknown status |
| Chonnam Natinal University Hospital Coordinator of this site? Confirm its status | Gwangju | South Korea | Unknown status |
| Chosun University Hospital Coordinator of this site? Confirm its status | Gwangju | South Korea | Unknown status |
| Wonkwang University Hospital Coordinator of this site? Confirm its status | Iksan | South Korea | Unknown status |
| Gachon University Gil Medical Center Coordinator of this site? Confirm its status | Incheon | South Korea | Unknown status |
| Gyeongsang National University Hospital Coordinator of this site? Confirm its status | Jinju | South Korea | Unknown status |
| Seoul National University Bundang Hospital Coordinator of this site? Confirm its status | Seongnam | South Korea | Unknown status |
| Korea Veterans Health Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Korea University Guro Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Kangbuk Samsung Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Korea University Anam Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Catholic University of Korea Seoul ST. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Gangnam Severance Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Severance hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Seoul National University Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Samsung Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Ewha Womans University Seoul Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Asan Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Chung-Ang University Hosptial Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| KyungHee University Hospital at GangDong Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Catholic University of Korea St. Vincent's Hospital Coordinator of this site? Confirm its status | Suwon | South Korea | Unknown status |
| Ulsan University Hospital Coordinator of this site? Confirm its status | Ulsan | South Korea | Unknown status |
| Wonju Severance Christian Hospital Coordinator of this site? Confirm its status | Wŏnju | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.