NCT05806775Completed
Low-load Resistance Training With Blood Flow Restriction in People With Parkinson's Disease
Feasibility of Low-load Resistance Training With Blood Flow Restriction in People With Advanced Disability Due to Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 18 Apr 2025
Brief summary (registry, in English)
The study's objective is to determine the feasibility of low-load resistance training with blood flow restriction in people who have advanced Parkinson's disease and impaired mobility using a mixed-methods convergent parallel design in a single cohort. The study's long-term goal is to develop clinically feasible exercise interventions that are effective at improving mobility, participation, and quality of life for people with advanced Parkinson's disease.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 24 Mar 2023
- Start date
- 1 Apr 2023
- Primary completion date
- 8 Nov 2024
- Lead sponsor
- University of Colorado, Denver
- Diseases
- Parkinson disease
- NCT number
- NCT05806775
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 1 Apr 2023 to the primary completion date, 8 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Using Blood Flow Restriction currently or in the previous 3 months prior to enrollment
- PD-related medication change in the month prior to enrollment
Other illness
- Unable to provide consent or diagnosis of dementia
- History of deep venous thrombosis/pulmonary embolism, peripheral vascular disease, thrombophilia or other clotting disorders; report of easy bruising
- Any comorbid conditions or pain that substantially affects ability to safely complete rehabilitation (e.g. neurologic, vascular, cardiac problems, orthopedic, or ongoing medical treatments) as determined by a neurologist or physical therapist
Other
- H\&Y Stage 1 (unilateral involvement only) or less
- H\&Y Stage 5 (wheelchair or bed bound)
- Currently undergoing supervised resistance training with a physical therapist or other exercise professional
- Cannot tolerate BFR pressure cuff inflated to 60% of total limb occlusion pressure during baseline assessment
Who the study is looking for
- Adults ages 18-89 with neurologist-confirmed diagnosis of PD
- H\&Y Stage 2 (bilateral involvement without postural instability) up to H\&Y Stage 4 (severe disease)
- Able to provide informed consent
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.