NCT05826379Enrolling by invitation
Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife
Mechanisms of Adherence to Light Intensity Physical Activity to Prevent Alzheimer's Disease and Related Dementias (ADRD)
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to determine whether interaction with an adaptive Fitbit-based goal setting application can increase levels of everyday light intensity physical activity in middle-aged adults.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 15 Mar 2023
- Start date
- 20 Mar 2024
- Primary completion date
- May 2027
- Lead sponsor
- Milton S. Hershey Medical Center
- Diseases
- Obesity, Alzheimer disease
- NCT number
- NCT05826379
What you commit to
- Study type: Interventional
- Planned participants: 200
- From 20 Mar 2024 to the primary completion date, May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Plan to have surgery or other procedure over the next 12 months that could affect mobility or light intensity physical activity maintenance
- Concurrent participation in a weight loss, physical activity, or cognitive training trial
Other illness
- Clinical diagnosis of ADRD or other neurodegenerative disease
- Health condition contraindicated for increased physical activity
- Medical conditions or medications that would prohibit participation in an exercise test (e.g., decompensated heart failure, severe aortic stenosis, uncontrolled arrhythmia, and acute coronary syndromes)
- Limitations in use of a smart phone (e.g., issues with manual dexterity or visual impairment)
- Failure to comply with Run-in Period activity monitoring (\<70% valid wear days for the Fitbit and activPal)
Other
- Inability to walk unassisted
- BMI \> 50
- Anyone who will not discontinue the use of their own personal smartwatch during the training period.
- Anyone who scores below 19 on the MoCA-B would not be randomized after the Run-in Calibration Period.
- Note: The eligibility criteria are deliberately incomplete to preserve the scientific integrity of the study. These details will be added after study closure.
Who the study is looking for
- Between 30 and 70 years of age
- BMI ≥ 25
Age in the registry: 30 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Milton S. Hershey Medical Center Coordinator of this site? Confirm its status | Hershey | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.