NCT05827237Completed
Rule Out of ACS in Primary Care Using a Decision Rule for Chest Pain Including Hs-troponin I POCT
Primary Care Decision Rule for Chest Pain Using the Marburg Heart Score and Hs-troponin I Point of Care Test to Rule Out Acute Coronary Syndrome
Source: ClinicalTrials.gov · Last updated 10 Sept 2025
Brief summary (registry, in English)
The goal of this clustered, diagnostic randomized controlled trial is to study a clinical decision rule including a high-sensitive troponin I point of care test in patients with chest pain in primary care. The main questions it aims to answer are: 1. Can unnecessary referrals to secondary care be reduced by the use of a clinical deci-sion rule in patients with new onset, non-traumatic chest pain in primary care? Compared to current daily practice. 2. What is the accuracy (sensitivity, negative prediction value) of the clinical decision rule for excluding ACS and MACE at 6 weeks and 6 months?
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 946 (actual)
- First submitted
- 21 Mar 2023
- Start date
- 18 Aug 2021
- Primary completion date
- 5 Feb 2025
- Lead sponsor
- Leiden University Medical Center
- Diseases
- Coronary artery disease
- NCT number
- NCT05827237
What you commit to
- Study type: Interventional
- Participants enrolled: 946
- From 18 Aug 2021 to the primary completion date, 5 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \<1 hour since onset of symptoms
- Inability to speak or understand Dutch
- Hemodynamic instability
Who the study is looking for
- ≥18 years of age
- Acute chest pain
- Seen by general practitioner
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Leiden University Medical Center Coordinator of this site? Confirm its status | Leiden | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.