NCT05834400Completed
Lymphatic System Stimulation in Heart Failure
Lymphatic System Stimulation and Fluid Overload Symptoms in Patients With Heart Failure
Source: ClinicalTrials.gov · Last updated 16 Apr 2026
Brief summary (registry, in English)
The goal of this pilot clinical trial is to obtain preliminary data on the effects of lymphatic exercise training in patients with heart failure. The main question[s] it aims to answer are: 1. Does performing lymphatic exercise decrease fluid overload symptoms (shortness of breath, lower legs swelling, fatigue), thoracic fluid content, and body fluid level? 2. Does performing lymphatic exercise improve sleep and quality of life (QOL)? Participants with heart failure will be randomly assigned into two groups: Group 1 will receive training on lymphatic exercises, and will perform these training for 4 weeks. This group will also be trained to monitor daily their weight, heart rate and blood pressure, and fluid overload symptoms. Group 2 will be trained to daily monitor their weight, heart rate and blood pressure, and fluid overload symptoms. This group will not perform the lymphatic exercises. Researchers will compare the two groups at the baseline and after delivering the 4 week-interventions to see 1. if lymphatic exercise helped decrease symptoms associated with fluid overload like shortness of breath, lower leg swelling, and fatigue. 2. if lymphatic exercises decreased thoracic fluid content and total body fluid level . 3. if the lymphatic exercise helped improve sleep and quality of life (QOL).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 3 Apr 2023
- Start date
- 15 Aug 2023
- Primary completion date
- 30 Sept 2025
- Lead sponsor
- Rutgers, The State University of New Jersey
- Diseases
- Heart failure
- NCT number
- NCT05834400
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From 15 Aug 2023 to the primary completion date, 30 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Received or waiting for heart transplantation
Other illness
- Severe liver or kidney insufficiency or malignant tumors
- A terminal condition with a life expectancy of < 6 months
- Cognitive impairment (e.g., dementia)
- Severe psychiatric condition (psychotic disorder, severe depression, suicidal intent)
Other
- Pregnancy
- Inability to converse in English
Who the study is looking for
- Clinical diagnosis of HF with New York Heart Association (NYHA) functional class II, III, or IV
- Willing and able to complete the home-based TOLF program upon discharge from the hospital to home
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cooper University Health Care (Cooper) Coordinator of this site? Confirm its status | Camden | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.