NCT05837507Terminated
Amyotrophic Lateral Sclerosis Non-invasive Ventilation Exchange
Contribution of a Multimodal Digital Platform in the Management and Follow-up of Patients With Amyotrophic Lateral Sclerosis Treated With Non-invasive Ventilation: Randomized Controlled Study
Source: ClinicalTrials.gov · Last updated 16 Jun 2026
Brief summary (registry, in English)
The median survival of patients with amyotrophic lateral sclerosis (ALS) is 3 to 5 years and mortality is mainly related to respiratory failure. Non-invasive ventilation (NIV) and multidisciplinary management improve the quality of life and survival of patients. However, patients have mobility difficulties related to the progressive worsening of functional disabilities. The research team hypothesize that the use of a multimodal digital platform, including in particular telemonitoring of NIV and teleconsultation, will slow down the evolution of the disabilities of patients with ALS and improve their quality of life.
- Status (registry)
- Terminated
- Study type
- Interventional
- Enrollment
- 43 (actual)
- First submitted
- 19 Apr 2023
- Start date
- 5 Jul 2023
- Primary completion date
- 21 Oct 2025
- Lead sponsor
- University Hospital, Montpellier
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT05837507
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with non-invasive ventilation in the previous three months
Other
- Refusal/inability to use a smart phone or digital device
- Patient currently participating or having participated in the month preceding inclusion in another clinical interventional research that could impact the study, this impact is left to the discretion of the investigator.
- Subject under guardianship or curators
- Subject not affiliated to a social security scheme, or not a beneficiary of such a scheme.
- Subject deprived of liberty by judicial or administrative decision
- Pregnant, parturient, breastfeeding women
- Refusal to give consent
Who the study is looking for
- Patients between 30 and 85 years old
- Diagnosis of ALS
- Indication and acceptance of non-invasive ventilation
- Patient equipped with suitable equipment (tablet, computer, telephone, etc.) with an internet connection at home
- Patient able to read and understand the procedure, and able to express consent for the study protocol
Age in the registry: 30 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinique du Millenaire | Montpellier | France | Unknown status |
| Uh Montpellier | Montpellier | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.