NCT05842057Active, not recruitingPhase 2
Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy
Phase 2 Randomized Trial: Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy (HAMMER)
Source: ClinicalTrials.gov · Last updated 14 Jul 2026
Brief summary (registry, in English)
The purpose of this research study is to evaluate if placing a dehydrated human amnion chorion membrane (dHACM) over the nerves after removal of the prostate during surgery (radical prostatectomy) will allow an earlier recovery of erectile function and urinary control after surgery.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 118 (actual)
- First submitted
- 24 Apr 2023
- Start date
- 24 Aug 2023
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- University of Miami
- Diseases
- Prostate cancer
- NCT number
- NCT05842057
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 118
- From 24 Aug 2023 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with complete, bilateral nerve resection.
- Previous treatment for prostate cancer.
- Previous history of pelvic radiation.
Other
- Men requiring the use of any non-oral erectile aids for erectile dysfunction (ED).
- Men with baseline EPIC26 scores \< 50.
- Patients with impaired decision-making capacity.
Who the study is looking for
- 1\. Men aged 40 to 80 years with localized prostate cancer who are undergoing RARP at the University of Miami (UM).
Age in the registry: 40 years to 80 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Miami Coordinator of this site? Confirm its status | Miami | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.