NCT05845203Completed
Ultrasound for Acute Field Triage of Stroke
Ultrasound for Acute Field Triage of Stroke: a Pilot Study- Ustrafast
Source: ClinicalTrials.gov · Last updated 16 Jun 2026
Brief summary (registry, in English)
Acute ischemic stroke (AIS) is responsible for considerable morbidity and mortality worldwide and has serious medico-economic and psychosocial consequences. Before the advent of mechanical thrombectomy (TM), care and telestroke networks had focused their efforts on the rapid administration of a thrombolytic agent, tissue plasminogen activator (tPA), intravenously ( IV), to all eligible patients with ischemic stroke. These care networks have been shown to improve both patient prognosis by improving early vascular recanalization, the overall quality of neurovascular care within the network, and costs at network hospitals. In 2015, the effectiveness of another treatment, TM, for some acute ischemic stroke patients with large vessel occlusion (LVO) created new challenges for the effective triage of suspected patients stroke, especially in the prehospital setting.Indeed, non-OLV patients should receive intravenous thrombolysis without delay and thus should be transported to the nearest facility with neurological capacity. thrombolysis.In contrast, the efficacy of thrombolysis remains limited for patients with LVO stroke who likely benefit from direct transport from the field to a comprehensive stroke center capable of performing TM. In these patients, stopping at a local center to initiate thrombolysis can delay revascularization and worsen the prognosis.These sorting strategy paradigms, called "mothership" and "drip and ship"
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 30 Mar 2023
- Start date
- 3 Oct 2023
- Primary completion date
- 10 Dec 2025
- Lead sponsor
- University Hospital, Tours
- Diseases
- Stroke
- NCT number
- NCT05845203
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 3 Oct 2023 to the primary completion date, 10 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of severe head trauma, or significant deformation of the skull.
Other
- (healthy subjects and patients)
- Realization of the transcranial Doppler likely to delay the treatment of the patient
- Patient eligible for thrombectomy. vs
- Major agitation (+3 on the Richmond Agitation Sedation Scale) (done only when the patient is agitated).
- Inability of the patient to consent due to the severity of the clinical symptoms, and the absence of an available relative.
- Recent craniofacial trauma with recent scalp or facial wounds.
Who the study is looking for
- Healthy subjects (recruitment via the CIC-IC):
- Adults (Age \>18),
- free from any known cerebral pathology,
- having given their informed, dated and signed free consent
- and affiliated with a French social security scheme (CMU accepted)
- Stroke topics:
- Adult patients (age \>18 years),
- admission for suspected stroke with a severity scale assessed by an NIH Stroke Scale \> 10 with or without signs of cortical damage.
- Onset of symptoms \< 24 hours.
- Proximal arterial occlusion confirmed by angio-MRI or angio-scan,
- free informed consent, dated and signed,
- affiliated to a French social security scheme (CMU accepted).
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| BOULOUIS Coordinator of this site? Confirm its status | Tours | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.