NCT05849155Recruiting
Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition
Source: ClinicalTrials.gov · Last updated 23 Apr 2026
Brief summary (registry, in English)
Testing children, adolescents, and young adults (CAYA) for a genetic risk for cancer can help with early prevention and detection of cancers through regular follow-ups and medical care. After receiving genetic test results, CAYA may not accurately understand what their results mean, and parents are often unsure about talking with their CAYA about their genetic risk for cancer. By understanding how parents communicate with their CAYA, the investigators can improve future genetic education to reduce cancer risk. Primary Objectives: * Identify qualities of parent-CAYA (child, adolescent, and young adults) communication about CAYAs' genomic cancer risk, and their association with CAYAs' psychosocial and prevention outcomes. * Examine the association between sociodemographic, cancer-related, and psychosocial factors and parent-CAYA communication regarding CAYAs' genomic risk for cancer. * Identify barriers and facilitators of parent-CAYA communication regarding CAYAs' genomic risk for cancer.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 125 (estimated)
- First submitted
- 25 Apr 2023
- Start date
- 12 Dec 2023
- Primary completion date
- Oct 2027
- Lead sponsor
- St. Jude Children's Research Hospital
- Diseases
- Childhood cancers
- NCT number
- NCT05849155
What you commit to
- Study type: Observational
- Planned participants: 125
- From 12 Dec 2023 to the primary completion date, Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient is only a carrier of a recessive variant that does not alone increase risk for cancer
- Patient's medical status or condition precludes completion of study (as determined by medical team, patient, or parent)
Age
- Participating caregiver is under the age of 18 years
Other
- Inability or unwillingness of patient or participating caregiver or to give informed consent/assent
- Patient or participating caregiver has evidence of significant cognitive deficits (per medical record) that would interfere with the ability to comprehend study questions
Who the study is looking for
- Patient aged 10 to 24 years (inclusive)
- Patient underwent germline genetic testing with a Pathogenic/Likely Pathogenic (P/LP) variant in a known cancer predisposition gene that increases risk for developing cancer
- P/LP result disclosed to the patient
- Patient has a primary caregiver willing to participate
- Patient and participating caregiver able to speak and read English
Age in the registry: 10 years to 24 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Jude Children's Research Hospital Coordinator of this site? Confirm its status | Memphis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.