Effect of rTMS of the Cerebellum on Parkinson's Disease

Prior treatment

• Increased risk of seizure for any reason, including prior diagnosis of increased intracranial pressure (such as after large infarctions or trauma), or currently taking medication that lowers the seizure threshold (assess via self report).
• Showed significant discomfort after receiving the rTMS treatment.

Other illness

• History or diagnosis of severe psychiatric disorders, such as depression, anxiety disorders, schizophrenia spectrum disorders, and bipolar disorders.
• Subjects with a clinically defined neurological disorder (assessed via self report) including, but not limited to: any condition likely to be associated with increased intracranial pressure, space occupying brain lesion, history of stroke, transient ischemic attack within two years, cerebral aneurysm, dementia, multiple sclerosis.
• Significant cognitive disorders (Mini-Mental State Exam (MMSE)\<24 points) or unable to complete the questionnaire independently.
• Intracranial implants, such as cochlear implants, aneurysms clips, shunts, stimulators, electrodes, cardiac pacemakers and vagus nerve stimulation devices.

Other

• Participated in other clinical trials.
• Inability to read or understand Chinese.

• Diagnosed with Parkinson's disease according to the clinical diagnostic criteria for Parkinson's disease (2015 edition) by the Movement Disorder Society (MDS)
• Citizens of the People's Republic of China of either sex, aged between 40 and 80 years.
• Able to give informed consent and follow the research plan.
• Hoehn-Yahr (H-Y) stage ≤ 3
• Patients received a Parkinson's stable medication before treatment (assessed via self report), which continued during treatment.