NCT05853887Active, not recruiting
Liquid Biopsy Based NGS in Newly Diagnosed NSCLC
iNUDGE: INtegration of liqUiD Biopsy Based Next Generation Gene sEquencing in Newly Diagnosed NSCLC - A Stepped Wedge Cluster Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 11 Mar 2026
Brief summary (registry, in English)
This study expands the application of an electronic health record (EHR) "nudge" used to prompt physicians' clinical practice to order molecular testing at the time of initial diagnosis for patients with specific types of advanced lung cancer. The primary goal is to have these test results available prior to starting treatment so that physicians can make molecularly-informed treatment decisions. The second goal is to better understand factors that contribute to whether or not the EHR-nudge implementation is successful.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 260 (actual)
- First submitted
- 7 Apr 2023
- Start date
- 15 Jun 2023
- Primary completion date
- 27 Feb 2026
- Lead sponsor
- Charu Aggarwal
- Diseases
- Lung cancer, Childhood cancers
- NCT number
- NCT05853887
What you commit to
- Study type: Interventional
- Participants enrolled: 260
- From 15 Jun 2023 to the primary completion date, 27 Feb 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Participants with incomplete staging information.
- Children, pregnant women, fetuses, neonates, or prisoners are not included in this research study.
Who the study is looking for
- Participants with a histological, or cytological diagnosis of metastatic non-squamous (mNSq) non-small cell lung cancer (NSCLC) who have not yet received systemic treatment for metastatic disease.
- Participants must be seen at Lancaster General Health (LGH), Penn Presbyterian Medical Center (PPMC), Penn Medicine Cherry Hill (PMCH), Penn Medicine Princeton Health (PMPH), Penn Medicine Voorhees (PMV) or Penn Medicine Washington Township (PMWT) for mNSq NSCLC.
Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penn Medicine Cherry Hill Coordinator of this site? Confirm its status | Cherry Hill | United States | Unknown status |
| Penn Medicine Lancaster General Health Coordinator of this site? Confirm its status | Lancaster | United States | Unknown status |
| Penn Presbyterian Medical Center Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Penn Medicine Princeton Health Coordinator of this site? Confirm its status | Plainsboro | United States | Unknown status |
| Penn Medicine Washington Township Coordinator of this site? Confirm its status | Sewell | United States | Unknown status |
| Penn Medicine Voorhees Coordinator of this site? Confirm its status | Voorhees Township | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.