NCT05857137Active, not recruiting
Psychosis TMS Study
Investigational TMS Study of Cognitive Impairment in Early Psychosis
Source: ClinicalTrials.gov · Last updated 11 Sept 2026
Brief summary (registry, in English)
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI. TMS is a noninvasive method used to modulate brain activity via changing magnetic fields applied over the surface of the scalp.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 4 May 2023
- Start date
- 4 Apr 2023
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Schizophrenia
- NCT number
- NCT05857137
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 4 Apr 2023 to the primary completion date, 30 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- TMS incompatibility including metallic implants in head and neck, cardiac pacemakers, history of seizures, pregnancy.
- MRI-incompatibility including implanted aneurism clips, cardiac pacemakers, metal implants, intrauterine devices, tattoos containing metal ink, pregnancy, and claustrophobia
- Unstable medical or neurologic illness that would preclude participation in study procedures
Other
- Severe substance abuse within 3 months (nicotine allowed)
Who the study is looking for
- Diagnosis of psychosis, psychosis not otherwise specified, schizophrenia, schizoaffective disorder, delusional disorder, bipolar disorder with psychosis, and schizophreniform disorder within first ten years of onset of psychotic symptoms.
- Ability to provide informed consent
Age in the registry: 18 years to 35 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Martinos Center for Biomedical Imaging Coordinator of this site? Confirm its status | Charlestown | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.