NCT05857475Completed
Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
Source: ClinicalTrials.gov · Last updated 5 Feb 2024
Brief summary (registry, in English)
To evaluate efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 3 Mar 2023
- Start date
- 1 Jun 2023
- Primary completion date
- 1 Dec 2023
- Lead sponsor
- Mahidol University
- Diseases
- COPD
- NCT number
- NCT05857475
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 1 Jun 2023 to the primary completion date, 1 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of COPD exacerbation during the past 8 week prior to inclusion.
- Subjects with acute or active respiratory infecton during 2 week prior to inclusion.
Other illness
- Subjects with recording history of chronic heart failure, significant arrhythmias, acute myocardial infarction, moderate to severe mitral or aortic valve disease and pulmonary hypertension.
- Subjects with interstitial lung disease.
- Subjects with neuromuscular disease.
- Subjects with chronic respiratory infection.
Lab values
- Subjects with chronic CO2 retension (PaCO2 \>/= 45 from arterial blood gas analysis) or Transcutaneous CO2 during sleep test \>/= 45 or Serum bicarbonate level \> 27
Other
- Diagnosis with \> 50% of central sleep apnea event
- Subjects who cannot perform spirometry test or walking test
- Subjects with morbid obesity (BMI \>/=35)
Who the study is looking for
- Diagnosis with COPD by GOLD guideline criteria (Post bronchodilator FEV1/FVC \< 0.7 or \< LLN) with post bronchodilator FEV1 = 30-80%
- Diagnosis with obstructive sleep apnea with AHI \> 15 event/hr. (Moderate OSA or more)
- Age between 40-80 years
- Stable disease prior to inclusion.
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Medicine Ramathibodi Hospital, Mahidol University Coordinator of this site? Confirm its status | Ratchathewi | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.