NCT05858437Recruiting
Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD
Impact of Propionic Acid on Regulatory T Cell Function in Children With Chronic Kidney Disease
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
Pro-Kids is a multi-center, double-blind, randomized and placebo-controlled intervention study in children with chronic kidney disease. The investigators address the effect of a dietary food supplementation of propionic acid on the immune system and the function of the intestinal barrier in CKD patients treated with hemodialysis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 16 (estimated)
- First submitted
- 25 Apr 2023
- Start date
- 15 Jan 2024
- Primary completion date
- 8 Jul 2026
- Lead sponsor
- Charite University, Berlin, Germany
- Diseases
- Chronic kidney disease
- NCT number
- NCT05858437
What you commit to
- Study type: Interventional
- Planned participants: 16
- From 15 Jan 2024 to the primary completion date, 8 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Immunosuppressive therapy within the last 12 weeks before the start of the study
- Pre-/pro- or postbiotic or antibiotic therapy within the last 4 weeks before the start of the study
- Planned or unplanned hospitalization within in last 4 weeks before the start of the study or during study
- alcohol- or drug abuse
Other illness
- Disease or dysfunctions, which disqualifies the patient
- Acute infections
- Malignant diseases
- chronic gastrointestinal or hepatic diseases (for example chronic inflammatory bowel disease
Other
- Incapacity of contract or any other circumstances, which prohibit the patient or his legal guardians from understanding setup, meaning and entity of the study
- Pregnancy
- parallel participation on other interventional trials
Who the study is looking for
- Body weight: \> 30kg
- CKD G5 treated with hemodialysis
- Continuous hemodialysis treatment for \> 3 months
- Clinical stable condition
- Manifestation of CKD within childhood (\<18 years)
Age in the registry: 12 years to 20 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Pediatric Gastroenterology, Nephrology and Metabolic Diseases, Charité-Universitätsmedizin Berlin Coordinator of this site? Confirm its status | Berlin | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.