NCT05860127Completed
Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
Cognitive Stimulation Therapy (CST) is an evidence-based non-pharmacological group therapy shown to benefit people with mild to moderate dementia. Despite increasing availability of CST worldwide, access remains limited in the United States. This pilot pragmatic trial will embed CST referral into the standard care protocol of health care settings that serve people living with dementia in the state of Connecticut, and evaluate online delivery of CST known as virtual CST (V-CST), and assess the acceptability of V-CST to people living with dementia. The study design is a two-armed randomized embedded pragmatic clinical trial (ePCT). The trial aims to determine if cognitive decline is experienced less commonly among V-CST participants than control group members based on three widely used measures of cognition, the Montreal Cognitive Assessment (MoCA), St. Louis University Memory Screen (SLUMS), and Mini Mental State Exam (MMSE). The study population will be persons with mild to moderate dementia identified by clinicians in standard care. From this population, subject participants will be randomized to intervention and control groups. Patients randomly assigned to the intervention group will be referred by their clinical providers to participate in V-CST, and those who accept the referral will participate in the intervention.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 133 (actual)
- First submitted
- 14 Feb 2023
- Start date
- 10 Apr 2023
- Primary completion date
- 12 Jun 2025
- Lead sponsor
- University of Massachusetts, Amherst
- Diseases
- Lewy body dementia, Alzheimer disease
- NCT number
- NCT05860127
What you commit to
- Study type: Interventional
- Participants enrolled: 133
- From 10 Apr 2023 to the primary completion date, 12 Jun 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient has previously participated in V-CST
Other illness
- Auditory or visual impairment, combative behaviors, or other clinician-assessed condition that would interfere with group treatment
Other
- No access to online meeting platform
- Patient has specified to HCS not to engage patient in research or to use patient data in research
- Physician determines a caregiver is needed to support V-CST participation, but no caregiver available to assist with technology.
Who the study is looking for
- Diagnosis of Mild Cognitive Impairment or Mild to Moderate Dementia
- MoCA score of 10 to 26 OR SLUMS score of 10 to 26 OR MMSE score between 13 and 24 recorded as present \< 24 months before the record review
- English-speaking
- Visit scheduled to include cognitive screening 6 to 12 months after record review.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UConn Center on Aging Coordinator of this site? Confirm its status | Farmington | United States | Unknown status |
| Yale Memory Clinic Coordinator of this site? Confirm its status | New Haven | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.