NCT05862792Completed
Liposomal Bupivacaine and Transoral Robotic Surgery
Impact of Liposomal Bupivacaine on Post-operative Pain, Opioid Use, and Swallow Function in Transoral Robotic Surgery
Source: ClinicalTrials.gov · Last updated 9 Oct 2026
Brief summary (registry, in English)
This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 39 (actual)
- First submitted
- 9 Jan 2023
- Start date
- 1 Jun 2023
- Primary completion date
- 2 Oct 2025
- Lead sponsor
- Geisinger Clinic
- Diseases
- Head and neck cancer
- NCT number
- NCT05862792
What you commit to
- Study type: Observational
- Participants enrolled: 39
- From 1 Jun 2023 to the primary completion date, 2 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with an allergy to Bupivacaine or other amide anesthetics; Patients with a carnitine deficiency
Who the study is looking for
- Adult patients, greater than or equal to 18 years of age; Patients of all genders; Patients undergoing transoral robotic surgery; Patient who are able and willing to give consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Geisinger Medical Center Coordinator of this site? Confirm its status | Danville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.