NCT05864729Completed
The Association Between Systemic Microvascular Endothelial Function and Coronary Physiology Indexes
Correlation Between Physiological Measures of Ischemia in the Hemodynamics Laboratory and Systemic Microcirculatory Parameters in Patients With Intermediate Lesions of the Main Coronary Arteries
Source: ClinicalTrials.gov · Last updated 26 Mar 2024
Brief summary (registry, in English)
The present study evaluates skin microvascular reactivity and coronary physiology in the same coronary artery disease (CAD) patients. This study is expected to find associations between systemic microvascular reactivity, measured non-invasively at the skin surface, and coronary reserve evaluated by the invasive angiographic method.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 8 May 2023
- Start date
- 1 Jun 2021
- Primary completion date
- 1 Dec 2023
- Lead sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
- Diseases
- Coronary artery disease
- NCT number
- NCT05864729
What you commit to
- Study type: Interventional
- Participants enrolled: 50
- From 1 Jun 2021 to the primary completion date, 1 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- ST elevation myocardial infarction in the first 72 hours of evolution.
- Allergy to contrast media or adenosine
- Asthma or chronic obstructive pulmonary artery disease diagnosis
- Ongoing acute coronary syndrome
- Baseline arrhythmias or advanced atrioventricular blockade
Lab values
- Renal failure (defined as serum creatinine above 1.5mg/dl)
Other
- Systolic blood pressure under 90mmHg
- Advanced arterial calcification
- Saphenous graft or mammary artery graft anastomosis stenosis
- Severe left ventricular systolic dysfunction.
Who the study is looking for
- Patients with intermediate obstructive coronary artery disease (40-80% lumen obstruction of epicardial vessels or 30-60% obstruction of left main coronary artery).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Institute of Cardiology Coordinator of this site? Confirm its status | Rio de Janeiro | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.