NCT05864794Recruiting
Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer
ValUe of Screening MRI Brain in Patients With Newly Diagnosed Stage IV Non-oncogene Addicted Non-small Cell Lung CANcer - The VULCAN Trial
Source: ClinicalTrials.gov · Last updated 9 Jun 2026
Brief summary (registry, in English)
Patients with newly diagnosed stage IV non-oncogene addicted NSCLC, who are fit for systemic treatment and don't have any symptoms of brain disease will undergo an MRI of the brain to screen for brain disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 17 Apr 2023
- Start date
- 13 May 2024
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- University Medical Center Groningen
- Diseases
- Lung cancer
- NCT number
- NCT05864794
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 13 May 2024 to the primary completion date, 31 Dec 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior/concomitant therapy for stage IV disease.
Lab values
- Oncogenic diver mutation (e.g. EGFR, ALK, ROS1, RET, MET, and BRAF) with approved targeted treatment.
Other
- Contraindications for MRI scan with contrast as per standard of care protocol of the institution.
Who the study is looking for
- Histologically or cytologically confirmed stage IV metastatic NSCLC, not amenable to curative treatment.
- Fit for systemic treatment (PS 0-2) according to standard of care.
- No symptoms of brain disease disease assessed according to standard clinical care by the thoracic oncologist.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Medical Center Groningen Coordinator of this site? Confirm its status | Groningen | Netherlands | Recruiting |
| Maastricht UMC Coordinator of this site? Confirm its status | Maastricht | Netherlands | Recruiting |
| Ommelander Ziekenhuisgroep Coordinator of this site? Confirm its status | Scheemda | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.