NCT05865405Active, not recruiting
A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis
Care Technology to Ascertain, Treat, and Engage the Community to Heal Depression in Patients With Multiple Sclerosis: Closing the Gaps in Depression Care for People With MS By Closing the Information Loop
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
The researchers want to find out if an electronic application called MS CATCH can enhance patients' and doctors' experiences during and in between clinical visits. MS CATCH is a smartphone-based tool which allows patients to enter their mood related symptoms at regular intervals, which is then available to their Neurologist in their electronic medical record. The neurologist is also able to view additional information from their medical record, and receives alerts for changes reported by the patient that raise concern for the patient's mental health.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 24 Apr 2023
- Start date
- 1 Aug 2023
- Primary completion date
- 15 Jan 2027
- Lead sponsor
- University of California, San Francisco
- Diseases
- Multiple sclerosis
- NCT number
- NCT05865405
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Aug 2023 to the primary completion date, 15 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive dexterity or visual impairment (typically defined as corrected acuity less than 20/70) that, in the opinion of the study neurologist (RB), would put the participant at risk or limit their ability to adhere to the study protocol
- Psychotic disorders: bipolar disorder, schizophrenia, schizoaffective disorder
Other
- Inability to provide informed consent
- Substance abuse that in the treating neurologist's perspective could influence the patient's safety on study or adherence to study protocol
- Another co-morbid CNS diagnosis eg. TBI
Who the study is looking for
- Diagnosis of MS (relapsing or progressive) by 2017 McDonald Criteria18
- Ages 18 to 80
- PHQ-9 score of 5-19
- Any MS therapy, or no treatment
- California resident to enable clinical telemedicine visits if warranted during the study visit
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Weill Institute for Neurosciences, University of California, San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.