NCT05865912Completed
A Feasibility Study of Mindfulness Training Transcranial Direct Current Stimulation (tDCS) in Adults With Overweight and Obesity
A Feasibility Study of Mindfulness Training Transcranial Direct Current Stimulation (tDCS) in Adults With Overweight and Obesity.
Source: ClinicalTrials.gov · Last updated 28 Jul 2025
Brief summary (registry, in English)
This study will investigate the feasibility of combining an app-based Mindfulness training (MT) with at-home administered transcranial direct current stimulation (tDCS) in adults with overweight or obesity and assess whether MT with tDCS may improve weight-related behaviours in this population. Specifically, the study will assess whether MT+ active tDCS, as opposed to MT+ sham tDCS or waiting list control, reduces high calorie food craving and consumption. Findings will inform the development of a future large-scale randomised controlled trial. The trial will be conducted in the UK.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 52 (actual)
- First submitted
- 11 Apr 2023
- Start date
- 17 Oct 2023
- Primary completion date
- 19 Feb 2025
- Lead sponsor
- King's College London
- Diseases
- Obesity
- NCT number
- NCT05865912
What you commit to
- Study type: Interventional
- Participants enrolled: 52
- From 17 Oct 2023 to the primary completion date, 19 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having any metallic implants in the head or body
- Significant health problems in the previous six months
- Taking psychotropic medication
- Taking medication for weight loss Regular, current or past, mindfulness meditation or yoga practice (defined as \> 20 minutes, twice or more per week during the past 2 months)
- Current illicit drug use
Other illness
- Pregnancy; history of neurological disease and/or seizure
- History of head or eye injury
- A lifetime diagnosis of substance dependence, psychosis, bipolar disorder, borderline personality disorder; any other primary psychiatric disorder requiring treatment in its own right
Other
- Insufficient written and spoken English
- All known contraindications to tDCS (Brunoni et al., 2012)
- Consuming more than 14 units of alcohol per week who are unwilling to reduce their alcohol intake for the duration of the treatment
- Learning difficulties that would preclude safe tDCS self-administration and/or completion of questionnaire measures and neurocognitive tasks (e.g.; working memory and inhibitory control)
- Current atypical anorexia nervosa or purging once a week or more.
Who the study is looking for
- Adults aged 18 to 60 w
- Overweight or obese (BMI ≥25 kg/ m2) according to World Health Organisation (WHO) criteria.
- Use and understand English as a language for everyday conversation.
- Have access to a laptop or desktop computer with webcam and to able to attend baseline, post intervention and follow up assessments in the Institute of Psychiatry, Psychology and Neuroscience (KCL).
Age in the registry: 18 years to 60 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CREW Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.