NCT05867381Recruiting
Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
Slowing Atherothrombosis Progression Through Indoor Air Filtration: A Crossover Trial in Hispanic and Non-Hispanic Adults With Ischemic Heart Disease History
Source: ClinicalTrials.gov · Last updated 8 Jun 2026
Brief summary (registry, in English)
This double-blind, randomized, crossover trial aims to test the hypothesis that longer-term indoor air filtration intervention can slow atherothrombosis progression by reducing indoor fine particulate matter (PM2.5) exposure in adults with ischemic heart disease history.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 112 (estimated)
- First submitted
- 23 Apr 2023
- Start date
- 11 Jul 2023
- Primary completion date
- 30 Jun 2028
- Lead sponsor
- University of Southern California
- Diseases
- Coronary artery disease
- NCT number
- NCT05867381
What you commit to
- Study type: Interventional
- Planned participants: 112
- From 11 Jul 2023 to the primary completion date, 30 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have history of degenerative disease of the nervous system such as dementia and Alzheimer's;
- Currently have active cancer treatments;
- Have any health conditions that prohibit collecting health and covariate data and biospecimens;
Other
- The residential house has already had HEPA filters;
- Participants will move out from the current residential address in the next 2 years;
- Participants will spend more than 1 month living outside the primary home;
- Participants' residential houses are not feasible for setting up air purifiers and air pollutants monitors.
Who the study is looking for
- Age between 65 and 84 years old;
- Weight ≥ 110 pounds;
- Nonsmokers for at least 1 year;
- Have ischemic heart disease history, clinically stable for 6 months, without any deterioration in symptoms or episodes of angina based on past electronic medical records;
- Both English and Spanish speaking participants will be included in the recruitment;
- Live in the Los Angeles County.
Age in the registry: 65 years to 84 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Keck School of Medicine, University of Southern California Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.