NCT05868616Recruiting
Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 26 Apr 2023
- Start date
- 21 Mar 2023
- Primary completion date
- Mar 2028
- Lead sponsor
- Oslo University Hospital
- Diseases
- Heart failure
- NCT number
- NCT05868616
What you commit to
- Study type: Observational
- Planned participants: 80
- From 21 Mar 2023 to the primary completion date, Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \< 18 years and \> 80 years;
Other
- Ongoing atrial fibrillation;
- Complete atrioventricular block
Who the study is looking for
- Patients referred for CRT implantation or postoperative control at Oslo University Hospital based on the European Society of Cardiology (ESC) guidelines (2021), and criteria below:
- Sinus rhythm.
- New York Heart Association class II / III heart failure on diagnosis and on optimal medical therapy.
- Left bundle branch block.
- QRS duration ≥ 130 ms.
- Left ventricular ejection fraction ≤ 40%.
- Patients must have echocardiography examination before implantation
- Informed consent obtained from the patient.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Oslo University Hospital Coordinator of this site? Confirm its status | Oslo | Norway | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.