NCT05880108Recruiting
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Source: ClinicalTrials.gov · Last updated 1 Jun 2026
Brief summary (registry, in English)
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older Veterans. Further, it will evaluate whether a weight loss intervention, including dietary modification and exercise, in obese Veterans with and without PCC will reduce systemic and adipose tissue inflammation and senescence and promote PCC recovery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 25 May 2023
- Start date
- 3 Jun 2024
- Primary completion date
- 30 Sept 2029
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Obesity, Long COVID and ME/CFS
- NCT number
- NCT05880108
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 3 Jun 2024 to the primary completion date, 30 Sept 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Self-reported alcohol or drug abuse
- Anti-coagulant medication usage
Other illness
- Neurologic, musculoskeletal, or other condition that limits subject's ability to complete study physical assessments
Lab values
- Active inflammatory, COVID-19, autoimmune, infectious, hepatic (LFTs \> 2.5 x WNL), renal (eGFR\<45), gastrointestinal, malignant, and psychiatric disease
- Uncontrolled diabetes (HbA1c \>10% or the current use of insulin)
Other
- Weight change within the past month of \>5 kg
Who the study is looking for
- U.S. Veteran
- Self-reported COVID-19 naïve or COVID-19 \> 90 days ago for lean and obese PCC naïve or documented COVID-19 for the lean and obese PCC groups (At least one PCC symptom \>4 weeks)
- Body Mass Index: 19-25 or 30-50 kg/m2
Age in the registry: - to 80 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
| South Texas Health Care System, San Antonio, TX Coordinator of this site? Confirm its status | San Antonio | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.