NCT05880758Recruiting
Impact of Yo-Yo Sleep on Cardiometabolic Health
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 72 (estimated)
- First submitted
- 17 May 2023
- Start date
- 22 Sept 2023
- Primary completion date
- Dec 2027
- Lead sponsor
- Columbia University
- Diseases
- Obesity
- NCT number
- NCT05880758
What you commit to
- Study type: Interventional
- Planned participants: 72
- From 22 Sept 2023 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pregnancy (current/prior year)
- Recent weight change or participation in a weight loss program or have ever had bariatric surgery or other weight loss or gastrointestinal procedure.
Other illness
- Sleep disorders
- Psychiatric disorders (including eating disorders) and seasonal affective disorder
- Diabetes
Lab values
- Individuals taking anti-coagulants or anti-platelets
Age
- Smokers (Any cigarette smoking or ex-smokers \<3years)
Other
- Breastfeeding
- Elevated blood pressure, taking beta-blockers
- Travel across time zones; shift work (non-traditional hours)
Who the study is looking for
- Aged 18 to 49 years
- BMI 20-29.9 kg/m2
- Habitually sleeping 7-9 hours/night without sleep aids or naps
Age in the registry: 18 years to 49 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Columbia University Irving Medical Center Coordinator of this site? Confirm its status | New York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.