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NCT05880940Completed

Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke

Source: ClinicalTrials.gov · Last updated 27 Feb 2026

Brief summary (registry, in English)

The purpose of this research study is to measure the effect of participating in extra arm exercise in addition to standard rehabilitation exercises in the Acute Rehabilitation Unit. This study will compare two different ways to perform the extra arm exercise. The first is following a customized program of hand and arm exercises that will be developed for study participants by an experienced rehabilitation therapist. The second is moving a participants arm back and forth when they are sitting in their wheelchair by using a moveable wheelchair arm rest (Boost).

Status (registry)
Completed
Study type
Interventional
Enrollment
35 (actual)
First submitted
26 Apr 2023
Start date
15 Sept 2023
Primary completion date
31 Jan 2025
Lead sponsor
University of California, Irvine
Diseases
Stroke
NCT number
NCT05880940

What you commit to

  • Study type: Interventional
  • Participants enrolled: 35
  • From 15 Sept 2023 to the primary completion date, 31 Jan 2025
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Subarachnoid hemorrhage
  • Presence of other neurological or psychological disorders affecting motor functions
  • Moderate to severe pain in the stroke-affected upper extremity (score \> 6 on 10-point visual analog pain scale), while using the movable wheelchair arm rest device
  • Severe aphasia (score of 2 or higher on the NIH stroke scale - question 9). PI may dismiss this criterion if the participant is deemed able to follow all study instructions.

Other

  • Severe tone at the affected upper extremity (score \> 4 on the Modified Ashworth Spasticity scale)
  • Deficits in vision, language, attention, neglect, or other cognitive functions severe enough to interfere with safe operation of wheelchair or the movable wheelchair arm rest device.
  • Currently pregnant
  • Difficulty in understanding or complying with instructions given by the experimenter.
  • Inability to perform the experimental task that will be studied.
  • Not part of another upper extremity motor-related interventional study

Who the study is looking for

  • 18 to 84 years of age
  • Experienced a single stroke or multiple strokes \>3 days and \< 4 weeks prior to study enrollment, and currently admitted or accepted into Acute Rehabilitation program for stroke.
  • UE Fugl-Meyer Motor Score \<42/66
  • Absence of moderate to severe shoulder pain while using the movable wheelchair arm rest device (\<6 on the 10-point visual analog pain scale)
  • Absence of severe tone at the affected UE (score \<4 on the Modified Ashworth Spasticity Scale)
  • Deem to be an appropriate candidate for manual wheelchair by ARU clinicians. A patient who has been able to transfer into a wheelchair while at ARU (with or without assistance) and has tolerated sitting in the wheelchair for at least 30 minutes.

Age in the registry: 18 years to 84 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Rancho Research Institute
Coordinator of this site? Confirm its status
DowneyUnited StatesUnknown status
University of California Irvine
Coordinator of this site? Confirm its status
OrangeUnited StatesUnknown status
Casa Colina Hospital and Centers for Healthcare
Coordinator of this site? Confirm its status
PomonaUnited StatesUnknown status

Related publications

This page is information, not medical advice. Discuss any trial with your doctor.