NCT05881252Completed
Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension
An Observational Study of Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension
Source: ClinicalTrials.gov · Last updated 28 Jul 2025
Brief summary (registry, in English)
The purpose of this study is observe outcomes before and after a change in clinical practice in the threshold for management of severe hypertension in pregnancy and the post-partum period. Outcomes will be observed for 10 months under the current (traditional) clinical blood pressure threshold for acute treatment of hypertension, which is \>= 160 millimeters of mercury (mmHg) systolic blood pressure (SBP). This will be followed by one month of education about rationale for the new SBP threshold of \>= 180 mmHg and change of clinical guidelines. Then, there will be 10 months of observation after adopting the updated clinical threshold for acute antihypertensive treatment (\>= 180 SBP).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1003 (actual)
- First submitted
- 18 May 2023
- Start date
- 11 May 2023
- Primary completion date
- 4 Apr 2024
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Diseases
- High blood pressure
- NCT number
- NCT05881252
What you commit to
- Study type: Observational
- Participants enrolled: 1003
- From 11 May 2023 to the primary completion date, 4 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active seizure, stroke, Congestive Heart Failure (CHF)/pulmonary edema, acute kidney injury (AKI), or myocardial infarction (MI)
- A history of stroke, CHF, chronic kidney disease (CKD), MI
Lab values
- Have Hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome or thrombocytopenia (platelets \< 100×10\^9/L)
Other
- Persistent neurologic symptoms including headache \>8/10 one hour after analgesic or blurry vision/loss of vision
Who the study is looking for
- any individual \> 20 weeks' gestation in triage or admitted at Children's Memorial Hermann Hospital (CMHH) and with blood pressure with \>= 160/110 mmHg
Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UT Houston Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.