NCT05884853Recruiting
The Plasticity of Social Brain Network in Adults With Autism Spectrum Disorder
Source: ClinicalTrials.gov · Last updated 31 Jul 2026
Brief summary (registry, in English)
"Social brain" refers to brain regions dedicated to processing social information and enabling us to recognize and evaluate others' mental states. The social brain hypothesis suggests that our brains evolve to navigate complex social systems. The social brain is hypothesized to consist of a distributed network including the posterior superior temporal sulcus (pSTS), the dorsal and ventral medial prefrontal cortices (dmPFC and vmPFC), ACC and posterior cingulate cortex (PCC), the amygdala, the orbital frontal cortex (OFC), and the fusiform gyrus (FG), TPJ, inferior occipital gyrus (IOG), and the insula. Each region serves distinct role while works together to support social processing, including perceiving, interpreting, and generating responses to the intentions, dispositions, and behaviors of others.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 4 May 2023
- Start date
- 1 Jan 2021
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Autism
- NCT number
- NCT05884853
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 1 Jan 2021 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- history of major mental illness, such as bipolar affective disorder, schizophrenia, psychosis, or neurological diseases
- visual impairment and/or hearing impairment
Other
- any metal, electronic part that cannot be removed from the body, or being pregnant, which may not be able to use fMRI scan.
Who the study is looking for
- age between 18 and 50
- diagnosed with ASD from licensed mental health or medical professional based on DSM5
- have social problems
- motivated to participate in the treatment
- fluent in chinese
- caregiver also fluent in chinese and motivated to participate
- had a full-scale IQ \> 70 on WAIS-IV
- scored ≧ 26 on the caregiver-reported Autism Spectrum Quotient (AQ), indicating clinical impairment associated with ASD.
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.