NCT05885646Recruiting
Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
Treatment of Epilepsy Syndromes of Childhood With Sleep Activation Using Sulthiame: an Exploratory Study of the Short Term Effect on EEG
Source: ClinicalTrials.gov · Last updated 15 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment. The aim of the study is to know if an effect is still identifiable after 2 weeks of treatment by performing sleep EEG recordings after 2 and 4 weeks of treatment, respectively.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 15 (estimated)
- First submitted
- 22 May 2023
- Start date
- 17 Oct 2023
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- University Hospital, Angers
- Diseases
- Epilepsy
- NCT number
- NCT05885646
What you commit to
- Study type: Observational
- Planned participants: 15
- From 17 Oct 2023 to the primary completion date, 1 Dec 2025
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous trial with sulthiame
- Use of corticosteroids at inclusion
- Change in the anti-epileptic treatment in the 7 days before baseline EEG
Other
- More than 2 AED at inclusion
Who the study is looking for
- Diagnosis of epilepsy syndromes of childhood with sleep activation
- Failure of at least two anti-epileptic drugs (AED)
- Sleep EEG performed in the last 7 days before inclusion and showing interictal epileptiform discharges (baseline EEG)
Age in the registry: 6 years to 15 years · Sex: All
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Angers University Hospital, Pediatric department Coordinator of this site? Confirm its status | Angers | France | Recruiting |
| Strasbourg University Hospital, Pediatric department Coordinator of this site? Confirm its status | Strasbourg | France | Not yet recruiting |
| Toulouse University Hospital, Pediatric Neurology Department Coordinator of this site? Confirm its status | Toulouse | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.