NCT05888623Completed
Computer Assisted Detection of Neoplasia During Colonoscopy Evaluation
Computer Assisted Detection of Neoplasia During Colonoscopy Evaluation (CADeNCE)
Source: ClinicalTrials.gov · Last updated 14 Oct 2025
Brief summary (registry, in English)
The goal of this cluster randomized study is to determine if artificial intelligence systems used during colonoscopy can improve the detection of precancerous polyps in the colon. The primary question it aims to answer is whether computer-assisted detection devices improve the proportion of colonoscopies found to have precancerous adenomatous polyps. Secondary aims will assess if computer-assisted detection devices improve the proportion of colonoscopies found to other types of precancerous polyps known as sessile serrated lesions, or cancer of the colon and rectum. The study will also assess possible negative effects of use of computer-assisted detection (e.g., prolonging the procedure time or false-positive biopsies) and survey device users to learn about their experience with this technology. The study team will provide computer-assisted detection devices to randomly chosen VA medical centers for use during colonoscopy and compare colonoscopy findings for patients who undergo colonoscopy at facilities that are equipped with these devices to the findings of patients who undergo colonoscopy at VA facilities that do not have these devices. A survey will be distributed to physicians who perform colonoscopy to assess their experience using computer-assisted detection devices.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 334200 (actual)
- First submitted
- 15 May 2023
- Start date
- 1 Oct 2022
- Primary completion date
- 30 Jun 2023
- Lead sponsor
- VA Puget Sound Health Care System
- Diseases
- Colorectal cancer, Childhood cancers
- NCT number
- NCT05888623
What you commit to
- Study type: Observational
- Participants enrolled: 334200
- From 1 Oct 2022 to the primary completion date, 30 Jun 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Colonoscopy performed at VA medical centers that acquired computer-assisted detection artificial intelligence devices through non-random assignment
- Colonoscopy performed at a VA medical center where pathology results are not available
Who the study is looking for
- Colonoscopy performed at a Veterans Affairs (VA) medical center
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| VA Puget Sound Health Care System Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
Related publications
- Impact of Availability of Computer-Aided Detection Devices on Adenoma Detection During Colonoscopy: A Cluster Randomized Study.Gastroenterology · 2026 · PMID 42250891
This page is information, not medical advice. Discuss any trial with your doctor.