NCT05889312Recruiting
Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET
Improving Response Assessment in Cancer by Measurement of Cellular Redox Status Using 18F-FSPG Positron Emission Tomography
Source: ClinicalTrials.gov · Last updated 4 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Prospective single centre non-randomised exploratory observational study to measure changes in tumour cellular redox status with 18F-FSPG PET in stage 3 non-small cell lung cancer (NSCLC) and stage 3 and 4 head and neck squamous cell cancer (HNSCC) at baseline and during standard of care treatment, and to compare this with 18F-FDG PET/CT and RECIST 1.1 response at 12 weeks.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 32 (estimated)
- First submitted
- 16 May 2023
- Start date
- 19 Feb 2025
- Primary completion date
- Sept 2026
- Lead sponsor
- Guy's and St Thomas' NHS Foundation Trust
- Diseases
- Childhood cancers
- NCT number
- NCT05889312
What you commit to
- Study type: Observational
- Planned participants: 32
- From 19 Feb 2025 to the primary completion date, Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant uncontrolled medical conditions
- Participants likely to require palliative radiotherapy within the first 12 weeks of treatment
- Previous anti-cancer treatment (only treatment naïve patients eligible for inclusion)
Other
- Pregnant or lactating women
- Prognosis less than 3 months
Who the study is looking for
- Written informed consent
- Aged 16 or above
- Histologically confirmed HNSCC or NSCLC, who are treatment naïve and scheduled to commence standard of care treatment ((chemo)radiotherapy)
- Willingness and ability to comply with scheduled study visits and tests
- Confirmation of adequate function of all major organs and systems
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guy's and St Thomas' NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.