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NCT05892952Recruiting

IONA Longitudinal Cohort Study

Source: ClinicalTrials.gov · Last updated 19 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Understanding more about how diseases that cause dementia develop is critical as the number of people living with, or affected by, dementia in Scotland continues to grow. The IONA Longitudinal Cohort Study (LCS) has been set up to gather information about people's cognitive health (their memory and thinking abilities), their lifestyle and health risk factors for future dementia (such as hearing loss and obesity), genetics and disease biomarkers, over a number of years. The IONA LCS has three main objectives: Firstly to develop this cohort that is well characterised (also known as being "well-phenotyped") that represent the Scottish population (taking into consideration age, sex, ethnicity and education). The second objective is to use this data to build disease models to better understand trajectories of diseases, and identify any sub-populations who have different (i.e. better, worse) disease trajectories. Finally the third objective for IONA LCS is to offer people an optional consent to hear about future studies they may be interested in taking part in.

Status (registry)
Recruiting
Study type
Observational
Enrollment
10000 (estimated)
First submitted
29 May 2023
Start date
21 Dec 2023
Primary completion date
21 Dec 2033
Lead sponsor
Brain Health Scotland Life Sciences Ltd
NCT number
NCT05892952

What you commit to

  • Study type: Observational
  • Planned participants: 10000
  • From 21 Dec 2023 to the primary completion date, 21 Dec 2033
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

  • Age at least 50 years.
  • Living in Scotland.
  • Able to read and write and with minimum 7 years of formal education.
  • Have a study partner who is aged 18 years or older.
  • Have capacity to provide informed consent at baseline.
  • Able to speak English to a level where the cognitive assessments can be completed.

Age in the registry: 50 years to 120 years · Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Scottish Brain Sciences Arran Facility
Coordinator of this site? Confirm its status
EdinburghUnited KingdomRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.