NCT05895032Completed
Trial of an Exercise Intervention for Children With Haemophilia
Development Of a haemophiLia PHysiotherapy INtervention for Optimum Musculoskeletal Health in Children (DOLPHIN-II) - a Randomised Controlled Trial
Source: ClinicalTrials.gov · Last updated 10 Sept 2026
Brief summary (registry, in English)
"Being able to participate in games and activities with their friends" is one of the things that matters most to boys with haemophilia. At present, there is a lack of robust evidence to determine whether muscle strengthening exercise can improve or negatively affect outcomes for young children with haemophilia. With the help of boys with haemophilia, their parents and physiotherapists the investigators have developed an exercise programme designed to increase muscle strength. Using this intervention the investigators will undertake a single-blinded, two-arm pragmatic randomised controlled trial (RCT) of a 12-week intervention verses usual care of boys with haemophilia aged 6-12 years of age.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 132 (actual)
- First submitted
- 21 Jul 2020
- Start date
- 6 May 2021
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- East Kent Hospitals University NHS Foundation Trust
- Diseases
- Haemophilia
- NCT number
- NCT05895032
What you commit to
- Study type: Interventional
- Participants enrolled: 132
- From 6 May 2021 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- orthopaedic surgery
Other illness
- von Willebrand disease
- past history of fracture or trauma to the lower limb
Other
- acquired brain injury or any other disturbance of the central nervous system; joint or muscle bleed in the lower limb in the past 6 weeks
- presence of lower limb pain or unable to fully comply with verbal instructions.
Who the study is looking for
- Children aged 6-12 years, with severe or moderate haemophilia A or B
Age in the registry: 6 years to 12 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Haemophilia Centre Coordinator of this site? Confirm its status | Canterbury | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.