NCT05896150Completed
Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection
Intercostal Cryoanalgesia for Management of Acute Postoperative Pain Following Video-assisted Thoracoscopic Lung Cancer Resection
Source: ClinicalTrials.gov · Last updated 4 Jul 2025
Brief summary (registry, in English)
Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the management of acute thoracic pain after VATS lung resection surgery.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 19 May 2023
- Start date
- 9 Nov 2023
- Primary completion date
- 22 Oct 2024
- Lead sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
- Diseases
- Lung cancer
- NCT number
- NCT05896150
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From 9 Nov 2023 to the primary completion date, 22 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgical criteria (conversion to thoracotomy, non anatomical wedge resection)
- Regular use of opioids or medication with effects against neuropathic pain (tricyclics, gabapentinoids, duloxetine, venlafaxine)
Other illness
- Known allergy to acetaminophen, celecoxib, sulfa or both hydromorphone and morphine
- History of thoracic surgery on the operated site
- Contraindication to non-steroidal anti-inflammatory drugs (renal filtration rate \< 60 mL/min, active gastric ulcer)
Other
- Contraindication to the paravertebral block (coagulopathy, discontinuous paravertebral space, impossible thoracoscopic visualization of the paravertebral space)
- Contraindication to intercostal cryoanalgesia (cold urticaria, cryoglobulinemia)
- Epidural analgesia preferred (high risk of thoracotomy, marginal lung function)
- Preoperative thoracic or shoulder pain on the operated side
- Inability to understand pain scales or to communicate clearly despite adequate teaching
- Pregnancy
- Patient refusal to participate
Who the study is looking for
- Patients scheduled for elective anatomical pulmonary resection (anatomical segmentectomy, lobectomy or bilobectomy) by VATS for lung cancer
- American Society of Anesthesiologists (ASA) score 1-3
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier de l'Université de Montréal Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.